Gastrointestinale Hormone

Gastrointestinale Hormone (Synonym: Enterohormone) werden von Zellen des Magen-Darm-Traktes sezerniert.^[1] Sie beeinflussen direkt und indirekt die Verdauung, metabolische Prozesse und sind gemeinsam mit nervaler Informationsübertragung an der Regulation von Hunger und Sättigung beteiligt.^[2]^[3] Ihre Wirkung kann sich endokrin, parakrin und autokrin entfalten.^[4] Wichtige gastrointestinale Hormone sind zum Beispiel Ghrelin, Gastrin, Sekretin, Cholecystokinin, GLP-1 und viele weitere. Auch Metabolite des Mikrobioms wirken als Hormone.^[5]

Einzelnachweise Bearbeiten

↑ Atsukazu Kuwahara, Kyoko Matsuda, Yuko Kuwahara, Shinji Asano, Toshio Inui: Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system. In: Biomedical Research (Tokyo, Japan). Band 41, Nr. 5, 2020, ISSN 1880-313X, S. 199–216, doi:10.2220/biomedres.41.199, PMID 33071256.
↑ Elena Valassi, Massimo Scacchi, Francesco Cavagnini: Neuroendocrine control of food intake. In: Nutrition, metabolism, and cardiovascular diseases: NMCD. Band 18, Nr. 2, Februar 2008, ISSN 1590-3729, S. 158–168, doi:10.1016/j.numecd.2007.06.004, PMID 18061414.
↑ Alyce M. Martin, Emily W. Sun, Damien J. Keating: Mechanisms controlling hormone secretion in human gut and its relevance to metabolism. In: The Journal of Endocrinology. Band 244, Nr. 1, 29. November 2019, ISSN 1479-6805, S. R1–R15, doi:10.1530/JOE-19-0399, PMID 31751295, PMC 6892457 (freier Volltext).
↑ Atsukazu Kuwahara, Kyoko Matsuda, Yuko Kuwahara, Shinji Asano, Toshio Inui: Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system. In: Biomedical Research (Tokyo, Japan). Band 41, Nr. 5, 2020, ISSN 1880-313X, S. 199–216, doi:10.2220/biomedres.41.199, PMID 33071256.
↑ Gerard Clarke, Roman M. Stilling, Paul J. Kennedy, Catherine Stanton, John F. Cryan: Minireview: Gut microbiota: the neglected endocrine organ. In: Molecular Endocrinology (Baltimore, Md.). Band 28, Nr. 8, August 2014, ISSN 1944-9917, S. 1221–1238, doi:10.1210/me.2014-1108, PMID 24892638, PMC 5414803 (freier Volltext).

[1] Atsukazu Kuwahara, Kyoko Matsuda, Yuko Kuwahara, Shinji Asano, Toshio Inui: Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system. In: Biomedical Research (Tokyo, Japan). Band 41, Nr. 5, 2020, ISSN 1880-313X, S. 199–216, doi:10.2220/biomedres.41.199, PMID 33071256.

[2] Elena Valassi, Massimo Scacchi, Francesco Cavagnini: Neuroendocrine control of food intake. In: Nutrition, metabolism, and cardiovascular diseases: NMCD. Band 18, Nr. 2, Februar 2008, ISSN 1590-3729, S. 158–168, doi:10.1016/j.numecd.2007.06.004, PMID 18061414.

[3] Alyce M. Martin, Emily W. Sun, Damien J. Keating: Mechanisms controlling hormone secretion in human gut and its relevance to metabolism. In: The Journal of Endocrinology. Band 244, Nr. 1, 29. November 2019, ISSN 1479-6805, S. R1–R15, doi:10.1530/JOE-19-0399, PMID 31751295, PMC 6892457 (freier Volltext).

[4] Atsukazu Kuwahara, Kyoko Matsuda, Yuko Kuwahara, Shinji Asano, Toshio Inui: Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system. In: Biomedical Research (Tokyo, Japan). Band 41, Nr. 5, 2020, ISSN 1880-313X, S. 199–216, doi:10.2220/biomedres.41.199, PMID 33071256.

[5] Gerard Clarke, Roman M. Stilling, Paul J. Kennedy, Catherine Stanton, John F. Cryan: Minireview: Gut microbiota: the neglected endocrine organ. In: Molecular Endocrinology (Baltimore, Md.). Band 28, Nr. 8, August 2014, ISSN 1944-9917, S. 1221–1238, doi:10.1210/me.2014-1108, PMID 24892638, PMC 5414803 (freier Volltext).

[1]

[2]

[3]

[4]

[5]